hellocare.ai, a digital health company developing AI-powered virtual care platforms, has announced a strategic collaboration with Mayo Clinic to co-develop artificial intelligence tools that improve efficiency, personalization, and clinical outcomes in virtual healthcare. The partnership aims to enhance virtual care delivery across provider organizations, with a shared focus on addressing the pressing need for scalable, value-based care models in a post-pandemic healthcare system.
The collaboration will leverage Mayo Clinic’s deep clinical expertise and global research leadership in partnership with hellocare.ai’s conversational AI platform and its proprietary multi-modal data integration engine. This union of capabilities is designed to create intelligent virtual agents that support healthcare providers and their patients throughout the care journey, from initial engagement to ongoing management of chronic diseases.

hellocare Smart Hospital Room
A New Model for AI-Driven Virtual Care
Virtual care has become an essential modality for healthcare delivery, particularly in managing chronic diseases, improving access, and reducing administrative burdens. However, providers continue to face challenges in scaling telehealth platforms while maintaining quality, clinical oversight, and patient engagement.
hellocare.ai’s platform uses generative AI to simulate natural conversations, enabling real-time clinical reasoning and personalized health navigation. Its co-innovation work with Mayo Clinic will target high-value use cases such as automating virtual intake, conducting post-discharge follow-ups, and supporting care coordination across multidisciplinary teams.
By combining natural language processing with medical knowledge graphs and structured clinical workflows, hellocare.ai aims to bridge the gap between consumer-grade virtual assistants and clinically safe, scalable virtual care delivery systems.
Mayo Clinic’s Expanding Role in Digital Health Innovation
This collaboration reflects Mayo Clinic’s broader commitment to advancing healthcare innovation through partnerships with health tech startups and emerging AI platforms. Mayo Clinic Platform, its flagship initiative for digital health innovation, has been instrumental in co-developing technologies that apply machine learning to remote monitoring, diagnostic support, and clinical decision-making.
Mayo Clinic’s involvement in this partnership will provide clinical guidance, access to datasets, and validation frameworks to help ensure that hellocare.ai’s tools are safe, evidence-based, and clinically effective.
“We are excited to collaborate with Mayo Clinic to co-innovate intelligent virtual care solutions that will empower clinicians and patients alike,” said Michael Gao, MD, co-founder and CEO of hellocare.ai. “Our shared vision is to make high-quality healthcare more accessible, proactive, and continuous.”
Industry Context: AI and Virtual Care on a Collision Course
The hellocare.ai-Mayo Clinic collaboration comes amid a rapid convergence of artificial intelligence and virtual care platforms. As the healthcare industry shifts toward value-based models, there is growing demand for intelligent systems that can automate routine tasks, close care gaps, and improve patient engagement without compromising safety.
Companies like Notable Health, Memora Health, and Aidoc have also entered this space, each targeting specific components of the virtual care workflow. However, hellocare.ai’s full-stack approach—combining conversational AI, clinical ontologies, and enterprise integrations—positions it to serve as a foundational layer for health systems aiming to transform their virtual care delivery models.
Unlike standalone chatbots or task-specific automation tools, hellocare.ai’s platform functions as a care navigation engine, adapting to multiple clinical contexts and aligning with health system goals such as readmission reduction, care gap closure, and cost containment.
Looking Ahead: Scalable, Human-Centered AI in Care Delivery
While the full scope of this collaboration has not yet been disclosed, it’s clear that the partnership is designed for long-term impact. Future phases may include integration with electronic health records (EHRs), care management platforms, and remote monitoring systems.
This aligns with a larger trend in healthcare AI: designing tools that not only augment clinicians but also act as connective tissue between patients, caregivers, and providers across the continuum of care.
As virtual care becomes a core channel for care delivery—particularly in primary care, behavioral health, and chronic condition management—this type of clinician-guided AI development is likely to shape the next generation of digital health infrastructure.
– This original article was created with AI support.