SEATTLE–(BUSINESS WIRE)–Kubota Vision Inc. (Kubota Vision), a clinical-stage specialty ophthalmology company and wholly-owned subsidiary of Kubota Pharmaceutical Holdings Co., Ltd. (Tokyo 4596), today announced the publication of a new paper in the journal Scientific Reports: Effect of short-term peripheral myopic defocus on ocular biometrics using Fresnel “press-on” lenses in humans. The paper was co-authored by Ryo Kubota, MD, PhD, Chairman, President and CEO of Kubota Vision, along with collaborators from the Manhattan Vision Associates / Institute for Vision Research (MVA) in New York City, and details the study results of axial length and choroidal thickness changes following short-term peripheral myopic defocus in normal adult subjects.
In this study, a total of 20 subjects enrolled and watched a full-field projected movie four meters away for four hours in the morning wearing corrected spectacle lenses for distance vision in both eyes. The right eye was peripherally defocused and tested with a Fresnel lens overlay of +3.50D with a central clear aperture of 11.5 mm (correlating to a clear central visual field of approximately 23 degrees), and the left eye was tested with no Fresnel lens overlay. Additional defocus sessions were conducted in 10 of these subjects with +5.00D of peripheral defocus in the right eye. Axial length and subfoveal choroidal thickness were measured and compared between the test (right) and control (left) eyes. The results demonstrated that short-term peripheral myopic defocus significantly inhibited axial elongation in adult humans, while no significant changes were observed in choroidal thickness.
The paper, titled “Effect of short-term peripheral myopic defocus on ocular biometrics using Fresnel ‘press-on’ lenses in humans,” is available in the online publication, Scientific Reports, at https://www.nature.com/articles/s41598-021-02043-2.
Scientific Reports, published by Springer Nature, is an open-access, peer-reviewed journal publishing original research from across all areas of the natural sciences, psychology, medicine, and engineering. It focuses only research that is scientifically robust, original, and of the highest quality, reviewed by its own extensive network of expert peers. In 2017, Scientific Reports became the largest journal in the world, overtaking PLOS ONE in the number of research articles published.*1
Dr. Kubota stated, “We are thrilled this paper to be in Scientific Reports and feel that the mechanism of Kubota Glass technology is now being recognized as the world-class innovation it is. Our continuous research will provide stronger scientific evidence to support Kubota Glass technology and expand our business opportunities in many countries.”
About Kubota Glass™ Technology
Kubota Glass technology works to reduce the increase in axial length associated with myopia by using myopically-defocused images on the peripheral visual field to stimulate the retina. Peripheral myopic defocus is already in use in the US with a contact lens, “MiSight® 1 day” by CooperVision, which is U.S. Food and Drug Administration (FDA) approved to slow the progression of myopia. Kubota Glass seeks to reduce the progression of myopia by stimulating the retina for shorter periods while maintaining high-quality central vision and not affecting daily activities.
About Kubota Vision Inc.
Kubota Vision Inc. is a wholly-owned subsidiary of Kubota Pharmaceutical Holdings Co., Ltd. (Tokyo 4596) committed to translating innovation into a diverse portfolio of drugs and devices to preserve and restore vision for millions of people worldwide. Kubota Pharmaceutical group’s development pipeline includes drug candidates for the treatment of diabetic retinopathy and Stargardt disease. The company is also developing a handheld OCT device for the monitoring of neovascular retinal diseases, to be used directly by patients, and wearable device for myopia control. https://www.kubotavision.com/; https://www.kubotaholdings.co.jp/en/
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Contacts
Media and Investor Relations Contact:
Yumiko Hamanaka
Corporate Planning Division
Phone: +81-3-6550-8928
Email: pr@kubotaholdings.co.jp